SIGN 135 Management of epithelial ovarian cancer
Ovarian cancer was the sixth most frequently diagnosed cancer in women in Scotland in 2011, representing 3.7% of all newly diagnosed cancers, and 583 new cases. Epithelial tumours account for over 90% of all ovarian cancers and are the focus of this guideline.
The overall incidence of ovarian cancer fell by 10.1% during the 10 years to 2011 and the overall five year survival rate improved from 25.7% among patients diagnosed in 1983-87 to 37.8% among patients diagnosed in 2003-2007. There is currently no recognised preventable cause and no effective screening programme, so earlier diagnosis and optimal management offer the best prospects for improving survival. Relapse is common, but surgery and chemotherapy can improve quality of life and prolong survival.
This guideline replaces SIGN 75 Management of epithelial cancer. New evidence and recommendations are presented relating to:
This guideline will be of interest to primary care staff, medical and clinical oncologists, gynaecologists, specialist nurses, community nurses, allied health professionals, geneticists, pathologists, specialists in laboratory medicine, pharmacists, radiologists, and palliative care specialists.