twitter logo youtube logo

Diagnosis and management of chronic kidney disease


Chronic kidney disease (CKD) is a long term condition caused by damage to both kidneys. There is no single cause and the damage is usually irreversible and can lead to ill health. The average prevalence has been reported at 11% in USA and Europe.

Remit and target users

This guideline covers the evidence for the association of specific risk factors with CKD to help identify which individuals are more likely to develop CKD. Guidance is provided on how to diagnose CKD principally using blood and urine tests. The guideline also contains recommendations on how to slow the progression of CKD and reduce the risk of cardiovascular disease.

This guideline will be of value to all health professionals in primary and secondary care involved in the detection and management of patients with CKD.

How this guideline was developed

This guideline was developed using a standard methodology based on a systematic review of the evidence. Further details can be found in SIGN 50: A Guideline Developer’s Handbook .

Keeping up to date

This guideline was issued in 2008 and will be considered for review in three years. The review history, and any updates to the guideline in the interim period, will be noted in the review report.

If you are aware of any new evidence that would update this guideline please complete a change request form  and return to:

>7 years

Use with caution, declaration of interests governance may not be in line with current policy.


Full guideline (PDF)

Quick reference guide (PDF)

Apple app

Android app

Supporting material

Register of Interests

Search narrative (PDF)

Equality Impact Assessment (PDF)

Polypharmacy Guidance (PDF)

Copyright permission (PDF)

Contact us

SIGN 103, June 2008
ISBN 978 1 905813 30 8

guidelines international network logo


HIS Healthcare Improvement Scotland logo