It is one thing to declare we are “adopting the GRADE principles”, but another to spell out exactly how we plan to do that. This section of the web site will build up over the next few months to highlight the changes we are making. For both users and those following our methodology, it would seem helpful to start with a clear statement of the principles on which our methodology is based.
SIGN guidelines are based on a systematic review of the evidence, undertaken by guideline development group members, with support from the SIGN Executive.
SIGN 50 is updated regularly to take into account any changes in methodology.
SIGN guidelines are developed using an explicit methodology based on three core principles:
These principles have remained constant since SIGN was first established.
Useful tools for critical appraisal
All in Acrobat pdf format (info)