The SIGN guide to the AGREE guideline appraisal instrument

[SIGN Guide to AGREE]

12. There should be an explicit link between the recommendations and the supporting evidence

When drawing conclusions from the evidence, aspects such as the volume of evidence, its applicability, generalisability, consistency and clinical impact should be taken into account. This is perhaps the most difficult part of the whole process, and requires the exercise of judgement based on experience as well as knowledge of the evidence and the methods used to generate it. Recommendations for clinical practice are derived from these evidence statements, with the key supporting references provided in the guideline.

Considered judgement form
Grading system
Example guideline extract

The SIGN Guide to the AGREE guideline appraisal instrument
Scottish Intercollegiate Guidelines Network (SIGN) 28 Thistle Street, Edinburgh EH2 1EN Tel. +44 (0) 131-718 5090 Fax. +44 (0) 131-718 5114 Website address: http://www.sign.ac.uk email sign@sign.ac.uk Last modified 6/6/05 © SIGN 2001