Guideline topic: Pharmacological management of asthma
Evidence table 4.11a: Add-on drugs for inhaled steroids: Chromones

Author

Year

Study type

Quality rating

Population

Outomes measured

Effect size

Confidence intervals / p values

Comments

O’Hickey¹

1994

RCT

+

Adults

Spirometry

am Pefr

pm Pefr

Symptoms


Bronchodilatorl use efficacy

Nil

22 l/min

16 l/min

-0.46 vs +0.09

Nil

p=0.06

p=0.07



p=0.03


p=0.03

Very small benefit from cromones