[Thistle]

Guideline topic: Pharmacological management of asthma
Evidence table 4.1: Inhaled short acting beta 2 agonists

Author

Year

Study type

Quality rating

Population

Outomes measured

Effect size

Confidence intervals / p values

Comments

Adults

Dennis S et al1

2000

RCT

++

Adult asthmatics with mild disease

Exacerbation rate, symptoms, PEF, b 2 agonist use

No difference in exacerbation rate

Yes

Results in agreement with Cochrane review.

Walters & Walters2

2000

Cochrane review

++

         
  1. Dennis SM, Sharp SJ, Vickers MR, Frost CD, Crompton GK, Barnes PJ, et al. Regular inhaled salbutamol and asthma control: the TRUST randomised trial. Therapy Working Group of the National Asthma Task Force and the MRC General Practice Research Framework. Lancet 2000;355(9216):1675-9.
  2. Walters EH, Walters J. Inhaled short acting beta2-agonist use in asthma: regular versus as needed treatment (Cochrane Review). In: The Cochrane Library, Issue 3, 2001. Oxford: Update Software.
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