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Management
of osteoporosis
|
Section 4.3.2 changed from
Calcium supplementation using tablets is one means of ensuring an adequate calcium intake in those unwilling or unable to do so by dietary means. A daily calcium intake of 1,000 mg or more taken in tablet form is likely to reduce fracture rates by a similar rate to that seen with dietary derived sources of calcium. There is no evidence that a vitamin D supplement is needed for active people under 65 years of age. However, everyone over 65 years of age should aim to take 10 mg (400 IU) daily of vitamin D. For the majority of people this can only be achieved by vitamin D supplementation.94 Where vitamin D deficiency has been confirmed or is likely, such as in the case of housebound individuals, a vitamin D supplement of 20 mg (800 IU) is the recommended dose.
to
Calcium supplementation using tablets is one means of ensuring an adequate calcium intake in those unwilling or unable to do so by dietary means. A daily calcium intake of 1,000 mg or more taken in tablet form is likely to reduce fracture rates by a similar rate to that seen with dietary derived sources of calcium. There is no evidence that a vitamin D supplement is needed for active people under 65 years of age. However, everyone over 65 years of age should aim to take 10 µg (400 IU) daily of vitamin D. For the majority of people this can only be achieved by vitamin D supplementation.94 Where vitamin D deficiency has been confirmed or is likely, such as in the case of housebound individuals, a vitamin D supplement of 20 µg (800 IU) is the recommended dose.
22 Oct 2003
Section 4.3.2 changed from
Calcium supplementation using tablets is one means of ensuring an adequate calcium intake in those unwilling or unable to do so by dietary means. A daily calcium intake of 1,000 mg or more taken in tablet form is likely to reduce fracture rates by a similar rate to that seen with dietary derived sources of calcium. There is no evidence that a vitamin D supplement is needed for active people under 65 years of age. However, everyone over 65 years of age should aim to take 10 mg (400 IU) daily of vitamin D. For the majority of people this can only be achieved by vitamin D supplementation.94 Where vitamin D deficiency has been confirmed or is likely, such as in the case of housebound individuals, a vitamin D supplement of 20 mg (800 IU) is the recommended dose.
to
Calcium supplementation using tablets is one means of ensuring an adequate calcium intake in those unwilling or unable to do so by dietary means. A daily calcium intake of 1,000 mg or more taken in tablet form is likely to reduce fracture rates by a similar rate to that seen with dietary derived sources of calcium. There is no evidence that a vitamin D supplement is needed for active people under 65 years of age. However, everyone over 65 years of age should aim to take 10 mg (400 IU) daily of vitamin D. For the majority of people this can only be achieved by vitamin D supplementation.94 Where vitamin D deficiency has been confirmed or is likely, such as in the case of housebound individuals, a vitamin D supplement of 20 µg (800 IU) is the recommended dose.
Section 6.8 changed from
In clinical trials bisphosphonates (alendronate, etidronate, or risedronate), raloxifene and calcitonin have usually been assessed in conjunction with calcium +/- vitamin D. Doses of calcium have varied from 500 to 1,000 mg and vitamin D from 6.25 to 20 mg (250 to 800 IU) per day. Where calcium intake is suboptimal (see section 4.3.2), daily doses of up to 1000mg calcium carbonate plus 20 mg (800 IU) vitamin D are appropriate for use in association with these drugs (in the absence of conditions associated with hypercalcaemia).
to
In clinical trials bisphosphonates (alendronate, etidronate, or risedronate), raloxifene and calcitonin have usually been assessed in conjunction with calcium +/- vitamin D. Doses of calcium have varied from 500 to 1,000 mg and vitamin D from 6.25 to 20 µg (250 to 800 IU) per day. Where calcium intake is suboptimal (see section 4.3.2), daily doses of up to 1000mg calcium carbonate plus 20 µg (800 IU) vitamin D are appropriate for use in association with these drugs (in the absence of conditions associated with hypercalcaemia).
4 Jul 2003
Amendments to Table 6
Row 4 changed from -
|
Vertebral fracture |
Risedronate118 |
1225 |
- |
8.4% over 3 years |
18.1% over 3 years |
0.51 (0.36,0.73) |
10 |
to
|
Vertebral fracture |
Risedronate118 |
1225 |
- |
29% over 3 years |
18.1% over 3 years |
0.51 (0.36,0.73) |
10 |
Row 10 changed from -
|
Hip fracture |
Alendronate 37 |
1640 |
Femoral neck T=<-2.5 |
2.2% over 4.2 years |
1% over 4.2 years |
0.44 (018,0.97) |
81 |
to
|
Hip fracture |
Alendronate 37 |
1640 |
Femoral neck T-=<-2.5 |
2.2% over 4.2 years |
1% over 4.2 years |
0.44 (0.18,0.97) |
81 |
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