Antithrombotic Therapy
Annex 2

Key points for audit of warfarin initiation in hospital183

PRACTICE POINT

AUDIT POINT

  • Objective test for diagnosis e.g. of venous thromboembolism
  • Appropriate investigation results documented e.g. ultrasound scanning and/or venography for deep venous thrombosis; chest x-ray and ventilation/perfusion scanning for pulmonary embolism
  • Baseline investigations.
  • Results of coagulation screen; blood count including platelet count; urea and electrolytes; liver function tests.
  • Risk factors for anticoagulation
  • Age, past history, drug history recorded
  • Start warfarin on day one of heparin administration (or confirmation of diagnosis).
  • First dose of warfarin on first day of heparin (or confirmation of diagnosis)
  • Overlap heparin and warfarin by 72 hours
  • Both heparin and warfarin prescribed concurrently for three days
  • Use algorithm to predict warfarin dose
  • Agreement of initial warfarin dose with that predicted from algorithm
  • Stop heparin when International Normalised Ratio (INR) within therapeutic range for two days
  • INR within target range for 2 days on day heparin stopped
  • Measure INR daily and at discharge
  • INR documented on each day of treatment; INR within target range on day of discharge; INR on day of discharge; time to achieve INR in target range
  • Anticoagulant management plan
  • Planned duration of anticoagulant treatment documented; target INR and range specified
  • Book appointment at anticoagulation clinic
  • Clinic appointment documented
  • Arrange interim INR if more than four days to clinic appointment
  • Arrangement for interim INR documented

[Contents][Back][Top] [Next]

Scottish Intercollegiate Guidelines Network
Home