Antithrombotic
Therapy
Annex
2
Key points for audit of warfarin initiation in hospital183
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PRACTICE POINT
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AUDIT POINT
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- Objective test for diagnosis e.g. of venous
thromboembolism
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- Appropriate investigation results documented
e.g. ultrasound scanning and/or venography for deep venous thrombosis;
chest x-ray and ventilation/perfusion scanning for pulmonary embolism
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|
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- Results of coagulation screen; blood count
including platelet count; urea and electrolytes; liver function
tests.
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- Risk factors for anticoagulation
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- Age, past history, drug history recorded
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- Start warfarin on day one of heparin administration
(or confirmation of diagnosis).
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- First dose of warfarin on first day of heparin
(or confirmation of diagnosis)
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- Overlap heparin and warfarin by 72 hours
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- Both heparin and warfarin prescribed concurrently
for three days
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- Use algorithm to predict warfarin dose
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- Agreement of initial warfarin dose with that
predicted from algorithm
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- Stop heparin when International Normalised
Ratio (INR) within therapeutic range for two days
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- INR within target range for 2 days on day heparin
stopped
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- Measure INR daily and at discharge
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- INR documented on each day of treatment; INR
within target range on day of discharge; INR on day of discharge;
time to achieve INR in target range
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- Anticoagulant management plan
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- Planned duration of anticoagulant treatment
documented; target INR and range specified
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- Book appointment at anticoagulation clinic
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- Clinic appointment documented
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- Arrange interim INR if more than four days
to clinic appointment
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- Arrangement for interim INR documented
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